:root{
  --navy:#030e1d;--navy-2:#071a34;--navy-3:#0b2242;--blue:#3558ff;--blue-2:#7691ff;--violet:#7657ff;
  --ink:#07111f;--muted:#667792;--muted-2:#91a0b8;--paper:#fff;--fog:#f4f7fb;--line:#ced8e8;--line-dark:#1d3c66;
  --green:#32bd87;--amber:#d99b16;--red:#d84f6d;--shadow:0 18px 60px rgba(3,14,29,.08);
  --serif:Georgia,'Times New Roman',serif;--sans:Arial,Helvetica,sans-serif;
  --shell:1280px;
}
*{box-sizing:border-box}
html{scroll-behavior:smooth;background:#e9eef5}
body{margin:0;background:var(--paper);color:var(--ink);font-family:var(--sans);font-size:16px;line-height:1.55;-webkit-font-smoothing:antialiased}
a{color:inherit;text-decoration:none}
img,svg{display:block;max-width:100%}
button,input,textarea,select{font:inherit}
button{cursor:pointer}
.sr-only{position:absolute!important;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}
.skip-link{position:fixed;left:16px;top:-60px;z-index:9999;background:#fff;color:#000;padding:12px 18px}.skip-link:focus{top:16px}
.shell{width:min(var(--shell),calc(100% - 80px));margin-inline:auto}
.site-header{height:86px;background:var(--navy);border-bottom:1px solid #14243a;color:#fff;position:relative;z-index:100}
.site-header__inner{height:100%;display:flex;align-items:center;justify-content:space-between;gap:40px}
.wordmark{display:block;width:150px;flex:0 0 auto}.wordmark img{width:100%;height:auto}
.site-nav{display:flex;align-items:stretch;height:100%;gap:4px}
.site-nav>a{display:flex;align-items:center;justify-content:center;position:relative;padding:0 17px;text-transform:uppercase;font-size:10px;line-height:1.05;letter-spacing:1.35px;color:#aab4c6;text-align:center;font-weight:700}
.site-nav>a:not(.nav-cta):not(.nav-room)::after{content:"";position:absolute;left:17px;right:17px;bottom:17px;height:2px;background:transparent}
.site-nav>a.is-active{color:#fff}.site-nav>a.is-active::after{background:var(--blue)}
.site-nav .nav-cta{height:64px;align-self:center;background:var(--blue);color:#fff;padding-inline:18px}
.site-nav .nav-room{height:64px;align-self:center;border:1px solid #72809a;color:#fff;padding-inline:13px}
.menu-toggle{display:none;background:none;border:0;padding:8px}.menu-toggle span{display:block;width:27px;height:2px;background:#fff;margin:6px 0}
.flash-stack{position:fixed;right:24px;top:104px;z-index:200;width:min(420px,calc(100% - 32px))}.flash{padding:15px 18px;background:#fff;border:1px solid var(--line);box-shadow:var(--shadow);margin-bottom:10px}.flash--success{border-left:4px solid var(--green)}.flash--error{border-left:4px solid var(--red)}
.hero{background:linear-gradient(108deg,var(--navy) 0%,#06162c 60%,#0a2450 100%);color:#fff;min-height:435px;display:flex;align-items:center;overflow:hidden}
.hero__grid{display:grid;grid-template-columns:1.1fr .9fr;gap:70px;align-items:center;padding-block:64px}
.hero__content{position:relative;z-index:2}.eyebrow{margin:0 0 18px;color:#7796ff;font-size:11px;line-height:1.3;text-transform:uppercase;letter-spacing:2.6px;font-weight:700}
.hero h1,.section h2,.auth-panel h1,.dashboard h1{font-family:var(--serif);font-weight:400;letter-spacing:-1.6px;line-height:1.03;margin:0}
.hero h1{font-size:72px;max-width:830px}.hero h1 em{font-style:normal;color:#7292ff}
.hero__copy{font-size:18px;line-height:1.65;color:#b4c0d3;max-width:720px;margin:24px 0 0}
.hero__actions{display:flex;gap:14px;margin-top:32px}.button{display:inline-flex;align-items:center;justify-content:center;min-height:54px;padding:0 30px;border:1px solid transparent;text-transform:uppercase;letter-spacing:.8px;font-size:11px;font-weight:700;transition:.2s ease}.button:hover{transform:translateY(-1px)}.button--primary{background:var(--blue);color:#fff}.button--outline{border-color:#70819d;color:#fff}.button--light{background:#fff;color:var(--blue)}.button--small{min-height:42px;padding-inline:20px}
.hero__visual{display:flex;justify-content:center;align-items:center;min-height:280px}.hero-visual-svg{width:100%;max-width:500px;height:auto}.trial-arm rect{fill:#071a34;stroke:#3558ff}.trial-arm text{fill:#fff;font-size:10px}.trial-arm text:first-of-type{fill:#8194b5;letter-spacing:1.2px;font-size:9px}
.status-bar{height:48px;background:#041021;color:#8f9bb0;border-top:1px solid #172a48;text-transform:uppercase;letter-spacing:.85px;font-size:9px;display:flex;align-items:center}.status-bar .shell{display:flex;align-items:center;gap:12px}.info-icon{display:inline-flex;align-items:center;justify-content:center;width:20px;height:20px;border:1px solid currentColor;border-radius:50%;font-size:11px;font-style:normal;flex:0 0 auto}
.subnav{height:56px;border-bottom:1px solid var(--line);background:#fff;position:sticky;top:0;z-index:50}.subnav .shell{height:100%;display:flex;align-items:center;gap:40px}.subnav a{position:relative;height:100%;display:flex;align-items:center;text-transform:uppercase;letter-spacing:1.2px;font-size:9px;color:#8997ad;font-weight:700}.subnav a.is-active{color:var(--blue)}.subnav a.is-active::after{content:"";position:absolute;left:0;right:0;bottom:0;height:2px;background:var(--blue)}
.section{padding:88px 0}.section--white{background:#fff}.section--fog{background:var(--fog)}.section--dark{background:var(--navy);color:#fff}.section--dark .section-heading>p,.section--dark .info-card p{color:#9aa9c0}.section--tight{padding:60px 0}.section--flush{padding:0}
.section-heading{display:grid;grid-template-columns:1.1fr .9fr;gap:80px;align-items:end;margin-bottom:40px}.section-heading h2{font-size:48px;max-width:800px}.section-heading>p{color:var(--muted);font-size:15px;line-height:1.65;margin:0 0 4px;max-width:610px}.section-heading.is-single{grid-template-columns:1fr}.section-heading.is-single>p{display:none}
.card-grid{display:grid;gap:18px}.cols-2{grid-template-columns:repeat(2,1fr)}.cols-3{grid-template-columns:repeat(3,1fr)}.cols-4{grid-template-columns:repeat(4,1fr)}.cols-5{grid-template-columns:repeat(5,1fr)}.cols-6{grid-template-columns:repeat(6,1fr)}
.info-card{border:1px solid var(--line);background:#fff;padding:28px 24px;min-height:170px;display:flex;flex-direction:column}.section--dark .info-card{background:var(--navy-2);border-color:#244468}.info-card h3{font:400 27px/1.18 var(--serif);margin:12px 0 12px}.info-card p{color:var(--muted);font-size:14px;line-height:1.65;margin:0}.info-card .text-link{margin-top:auto;padding-top:16px;color:var(--blue);font-size:10px;letter-spacing:1.2px;text-transform:uppercase;font-weight:700}.card-number{font:400 38px/1 var(--serif);color:var(--blue);margin-bottom:14px}.card-tag{display:block;border:1px solid #91a4ff;color:var(--blue);background:#f1f4ff;padding:5px 9px;font-size:9px;text-transform:uppercase;letter-spacing:1.2px}.section--dark .card-tag{background:transparent;border-color:#365b8c;color:#94a8ff}
.notice{display:flex;gap:14px;border:1px solid var(--line);padding:18px 20px;align-items:flex-start}.notice p{margin:0;color:var(--muted);font-size:13px;line-height:1.55}.notice--blue{background:#edf1ff;border-left:4px solid var(--blue)}.notice--dark{background:var(--navy-2);border-color:#294a78;color:#9daec5}.notice--dark p{color:#9daec5}
.check-list{list-style:none;padding:0;margin:0;display:grid;gap:15px}.check-list li{display:flex;gap:13px;align-items:flex-start}.check-list li>span{width:20px;height:20px;border:1px solid #6f8eff;color:var(--blue);border-radius:50%;display:inline-flex;align-items:center;justify-content:center;font-size:10px;flex:0 0 auto}.check-list strong{display:block;font-size:13px}.check-list small{display:block;color:var(--muted);font-size:11px;line-height:1.5;margin-top:2px}
.split{display:grid;grid-template-columns:1.1fr .9fr;gap:54px;align-items:start}.split--equal{grid-template-columns:1fr 1fr}.split--wide-right{grid-template-columns:.85fr 1.15fr}.split--wide-left{grid-template-columns:1.2fr .8fr}
.panel{border:1px solid var(--line);padding:28px;background:#fff}.section--dark .panel{background:var(--navy-2);border-color:#294a78}.panel h3{font:400 28px/1.2 var(--serif);margin:0 0 20px}
.form-card{background:var(--navy);border:1px solid #2b4b76;color:#fff;padding:32px}.form-card h3{font:400 32px/1.1 var(--serif);margin:0 0 8px}.form-card>p{margin:0 0 24px;color:#9eacc0;font-size:13px}.form-grid{display:grid;gap:14px}.form-field{display:block}.form-field>span{display:block;text-transform:uppercase;letter-spacing:1px;font-size:9px;color:#9dadc2;margin:0 0 7px}.form-field input,.form-field textarea,.form-field select{width:100%;border:1px solid #31517b;background:#0b203f;color:#fff;min-height:48px;padding:12px 14px;outline:none;border-radius:0}.form-field textarea{min-height:115px;resize:vertical}.form-field input:focus,.form-field textarea:focus,.form-field select:focus{border-color:#6e8fff;box-shadow:0 0 0 2px rgba(53,88,255,.18)}.form-card .button{width:100%;margin-top:4px}.honeypot{position:absolute!important;left:-9999px!important;opacity:0!important}
.stage-line{display:grid;grid-template-columns:repeat(var(--stages,6),1fr);position:relative;gap:0;margin-top:24px}.stage-line::before{content:"";position:absolute;top:8px;left:8px;right:8px;height:2px;background:#c6d0df}.stage-node{position:relative;padding-top:25px;text-align:center;color:#8b98ac;font-size:9px}.stage-dot{position:absolute;top:2px;left:50%;width:13px;height:13px;margin-left:-6.5px;border-radius:50%;background:#fff;border:2px solid #bdc9dc;z-index:2}.stage-node.is-complete .stage-dot,.stage-node.is-current .stage-dot{background:var(--blue);border-color:var(--blue)}.stage-node.is-complete~.stage-node:before{background:transparent}.stage-node strong{font-size:9px;color:var(--ink)}.section--dark .stage-line::before{background:#264266}.section--dark .stage-dot{background:var(--navy);border-color:#52647d}.section--dark .stage-node strong{color:#fff}
.hero-pipeline-visual{width:100%;max-width:560px}.hp-row{display:grid;grid-template-columns:100px 1fr;gap:20px;align-items:start;margin:0 0 42px;color:#b2bfd0;font-size:12px}.hp-row .stage-line{margin:0;--stages:6}.hp-note{margin-left:120px;border:1px solid #31517b;background:#071a34;padding:16px 20px}.hp-note strong{display:block;color:#7691ff;font-size:9px;letter-spacing:2px}.hp-note small{display:block;color:#a5b1c4;margin-top:6px}
.capsule-visual{width:100%;max-width:520px;display:flex;flex-direction:column;align-items:center;gap:24px}.capsule-body{width:300px;height:118px;background:#f2f5fb;border-radius:70px;transform:rotate(-17deg);box-shadow:inset -16px -12px 30px rgba(7,17,31,.08),0 15px 30px rgba(0,0,0,.18);position:relative;color:#09111d}.capsule-body::after{content:"";position:absolute;left:50%;top:0;bottom:0;width:1px;background:#b8c5d8}.capsule-body span{position:absolute;right:25px;top:37px;transform:rotate(17deg);font-size:13px}.capsule-body b,.capsule-body small{display:block}.capsule-body small{font-size:11px;font-weight:400;margin-top:3px}.dose-timeline{width:420px;border:1px solid #31517b;background:#071a34;padding:13px 18px}.dose-timeline>strong{display:block;color:#7691ff;font-size:8px;letter-spacing:2px}.dose-timeline>div{height:18px;display:flex;align-items:center;justify-content:space-between;position:relative}.dose-timeline>div::before{content:"";position:absolute;left:2px;right:2px;height:1px;background:#385587}.dose-timeline i{width:8px;height:8px;border-radius:50%;background:#3558ff;z-index:1}.dose-timeline i:last-child{background:#7657ff}.dose-timeline small{display:flex;justify-content:space-between;color:#7588a6;font-size:7px}
.paper-stack{position:relative;width:460px;height:285px}.paper{position:absolute;background:#fff;border:1px solid #d4dce9;box-shadow:0 8px 22px rgba(0,0,0,.09)}.paper--back{width:245px;height:245px;right:104px;top:30px;transform:rotate(-4deg)}.paper--mid{width:245px;height:245px;right:86px;top:18px;transform:rotate(3deg)}.paper--front{width:250px;height:255px;right:75px;top:8px;padding:24px 22px;color:var(--ink);z-index:2}.paper--front small{color:#6b84ff;font-size:8px;letter-spacing:1.7px}.paper--front strong{display:block;font:400 22px/1.15 var(--serif);margin:14px 0}.paper--front i{display:block;height:1px;background:#d8dfeb;margin:12px 0}.paper--front b{display:inline-flex;background:var(--blue);color:#fff;font-size:8px;padding:11px 15px;margin-top:13px}.eye-card{position:absolute;right:0;top:70px;width:88px;height:88px;border:1px solid #3558ff;border-radius:8px}.eye-card i{position:absolute;left:20px;top:28px;width:48px;height:30px;border:2px solid #7592ff;border-radius:50%}.eye-card i::after{content:"";position:absolute;left:17px;top:7px;width:12px;height:12px;border-radius:50%;background:#3558ff}.paper-stack em{position:absolute;right:1px;top:170px;color:#6f83a4;font-style:normal;font-size:8px;letter-spacing:1.5px}
.record-card{display:grid;grid-template-columns:190px 1fr;gap:25px;border:1px solid var(--line);padding:22px}.record-card__thumb{border:1px solid var(--line);background:#fff;padding:10px}.record-card__thumb img{width:100%}.record-card h3{font:400 30px/1.1 var(--serif);margin:7px 0 10px}.record-meta{display:grid;grid-template-columns:repeat(3,1fr);gap:18px;border-top:1px solid var(--line);padding-top:14px;margin-top:18px}.record-meta strong{display:block;font-size:10px}.record-meta span{display:block;color:var(--muted);font-size:11px}
.legend{display:flex;flex-wrap:wrap;gap:16px;font-size:10px;color:var(--muted)}.legend i,.evidence-dot{display:inline-block;width:8px;height:8px;border-radius:50%;margin-right:5px}.dot-blue{background:var(--blue)}.dot-green{background:var(--green)}.dot-purple{background:var(--violet)}.dot-amber{background:var(--amber)}.dot-gray{background:#9ca9bc}.dot-red{background:var(--red)}
.metrics{display:grid;grid-template-columns:repeat(2,1fr);gap:22px}.metric strong{font:400 42px/1 var(--serif);color:var(--blue);display:block}.metric span{color:var(--muted);font-size:11px}
.viewer-layout{display:grid;grid-template-columns:330px 1fr;gap:38px;align-items:start}.record-sidebar{display:grid;gap:18px}.viewer-shell{border:1px solid #bac7da;background:#d4dce7;min-width:0}.viewer-toolbar{height:48px;background:#1a2839;color:#c9d2df;display:flex;align-items:center;justify-content:space-between;padding:0 20px;font-size:11px}.viewer-toolbar__controls{display:flex;gap:16px;align-items:center}.viewer-main{display:grid;grid-template-columns:190px minmax(0,1fr) 210px;min-height:745px}.viewer-outline,.viewer-claims{background:#edf1f6;padding:20px;font-size:11px;color:#5f708a}.viewer-outline strong,.viewer-claims strong{color:#243247;display:block;margin-bottom:12px}.viewer-outline a{display:block;margin:7px 0}.viewer-page-stage{display:flex;align-items:flex-start;justify-content:center;padding:28px;background:#c8d1de;overflow:auto;min-height:745px}.viewer-page{width:min(100%,560px);background:#fff;box-shadow:0 1px 3px rgba(0,0,0,.12)}.viewer-page img{width:100%}.viewer-badge{display:block;border:1px solid;padding:5px 8px;text-transform:uppercase;letter-spacing:1px;font-size:8px;margin-bottom:7px}.viewer-badge.green{border-color:#76d2ad;color:#15865a;background:#ebfbf5}.viewer-badge.amber{border-color:#edc46d;color:#9a6a00;background:#fff8e9}.viewer-badge.red{border-color:#ee9bad;color:#b2334f;background:#fff0f3}.claim-list{border-top:1px solid #ced7e3;margin-top:20px;padding-top:17px}.claim-list p{font-size:10px;line-height:1.55}.linked-file{display:block;border:1px solid #cad4e2;background:#fff;padding:10px;margin:8px 0}.viewer-footnote{margin-top:16px}
.table-wrap{overflow:auto}.data-table{width:100%;border-collapse:collapse;font-size:12px;min-width:820px}.data-table th{text-align:left;color:#75849a;text-transform:uppercase;letter-spacing:1px;font-size:9px;padding:13px 12px;border-bottom:1px solid #bdc9d9}.data-table td{padding:15px 12px;border-bottom:1px solid #dbe2ec;vertical-align:top}.status-pill{display:inline-flex;border:1px solid #91a4ff;color:var(--blue);background:#f1f4ff;padding:6px 8px;text-transform:uppercase;font-size:8px;letter-spacing:.9px}.status-pill.green{color:#13845b;border-color:#76d2ad;background:#edfbf6}.status-pill.amber{color:#9a6a00;border-color:#e5b85b;background:#fff8e8}.status-pill.red{color:#ae3652;border-color:#eb91a6;background:#fff0f3}
.auth-page{min-height:100vh;background:linear-gradient(108deg,var(--navy) 0 60%,#0a2450);display:grid;place-items:center;padding:40px;color:#fff}.auth-panel{width:min(450px,100%);border:1px solid #31517b;background:#06162c;padding:40px}.auth-panel .wordmark{width:160px;margin:0 0 28px}.auth-panel h1{font-size:46px;margin:26px 0 14px}.auth-panel p{color:#9eacc0}.auth-panel .form-grid{margin-top:28px}.auth-panel hr{border:0;border-top:1px solid #274669;margin:25px 0}.auth-label{display:block;background:#eff2ff;color:var(--blue);padding:7px 12px;font-size:9px;text-transform:uppercase;letter-spacing:1.5px}.auth-note{text-align:center;font-size:12px}.auth-disclaimer{font-size:10px!important}
.portal{min-height:100vh;background:#edf2f8;display:grid;grid-template-columns:235px minmax(0,1fr)}.portal-sidebar{background:var(--navy);color:#9eacc0;padding:26px 20px;position:sticky;top:0;height:100vh}.portal-sidebar .wordmark{width:145px;margin:0 0 35px}.portal-nav{display:grid;gap:5px}.portal-nav a{display:block;padding:13px 14px;font-size:12px;border-radius:3px}.portal-nav a.is-active{background:#102b51;color:#fff}.portal-main{padding:30px 34px 50px;min-width:0}.portal-head{display:flex;align-items:start;justify-content:space-between;gap:30px;margin-bottom:26px}.portal-head h1{font:400 42px/1 var(--serif);margin:0 0 7px}.portal-head p{color:var(--muted);margin:0}.portal-metrics{display:grid;grid-template-columns:repeat(4,1fr);gap:16px;margin-bottom:20px}.portal-metric{background:#fff;border:1px solid var(--line);padding:26px 18px}.portal-metric strong{font:400 42px/1 var(--serif);color:var(--blue);display:block}.portal-metric span{font-size:10px;color:var(--muted);text-transform:uppercase;letter-spacing:1px}.portal-panel{background:#fff;border:1px solid var(--line);padding:24px;margin-bottom:20px}.portal-panel h2{font:400 31px/1.1 var(--serif);margin:0 0 22px}.folder-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:18px}.folder-card{border:1px solid var(--line);padding:22px;min-height:180px}.folder-card h3{font:400 20px/1.2 var(--serif);margin:14px 0 10px}.folder-card p{color:var(--muted);font-size:13px}.admin-grid{display:grid;grid-template-columns:1fr 320px;gap:22px}.admin-form{display:grid;gap:14px}.admin-form label span{display:block;color:#65758e;font-size:10px;text-transform:uppercase;letter-spacing:1px;margin-bottom:6px}.admin-form input,.admin-form textarea,.admin-form select{width:100%;border:1px solid var(--line);padding:12px 13px;background:#fff}.admin-form textarea{min-height:90px}.admin-actions{display:flex;gap:10px;margin-top:14px}.admin-actions button,.admin-actions a{border:0;background:var(--blue);color:#fff;padding:12px 20px;font-size:11px;text-transform:uppercase;font-weight:700}.admin-actions .secondary{background:#fff;border:1px solid var(--line);color:var(--ink)}
.site-footer{background:#020c19;color:#8795aa;padding:65px 0 18px}.site-footer__grid{display:grid;grid-template-columns:2fr repeat(4,1fr);gap:54px}.wordmark--footer{width:150px;margin-bottom:18px}.footer-brand p{max-width:360px;font-size:11px;line-height:1.7}.site-footer__grid>div:not(.footer-brand){display:flex;flex-direction:column;gap:8px}.site-footer strong{color:#fff;text-transform:uppercase;letter-spacing:1.1px;font-size:9px;margin-bottom:8px}.site-footer a{font-size:10px}.site-footer a:hover{color:#fff}.site-footer__bottom{margin-top:48px;padding-top:16px;border-top:1px solid #15243b;display:flex;justify-content:space-between;font-size:8px}
@media(max-width:980px){
 .shell{width:min(100% - 34px,var(--shell))}.site-header{height:75px}.site-header .wordmark{width:120px}.menu-toggle{display:block}.site-nav{display:none;position:absolute;top:75px;left:0;right:0;height:auto;background:#051326;padding:15px;flex-direction:column;align-items:stretch}.site-nav.is-open{display:flex}.site-nav>a{min-height:48px;justify-content:flex-start;text-align:left;padding-inline:18px}.site-nav .nav-cta,.site-nav .nav-room{height:52px;align-self:stretch;justify-content:center}.hero{min-height:auto}.hero__grid{grid-template-columns:1fr;gap:28px;padding:42px 0 34px}.hero h1{font-size:52px;letter-spacing:-1.2px}.hero__copy{font-size:15px}.hero__visual{min-height:220px}.status-bar{height:auto;min-height:40px;padding:10px 0}.subnav{overflow-x:auto;position:relative}.subnav .shell{gap:28px;width:max-content;padding:0 17px}.section{padding:58px 0}.section-heading{grid-template-columns:1fr;gap:18px}.section-heading h2{font-size:39px}.split,.split--equal,.split--wide-right,.split--wide-left{grid-template-columns:1fr}.cols-5,.cols-6{grid-template-columns:repeat(2,1fr)}.cols-4{grid-template-columns:repeat(2,1fr)}.site-footer__grid{grid-template-columns:1.5fr repeat(2,1fr)}.viewer-layout{grid-template-columns:1fr}.record-sidebar{grid-template-columns:repeat(2,1fr)}.portal{grid-template-columns:1fr}.portal-sidebar{position:relative;height:auto}.portal-nav{display:flex;overflow:auto}.portal-main{padding:22px 18px}.portal-metrics,.folder-grid{grid-template-columns:repeat(2,1fr)}.admin-grid{grid-template-columns:1fr}
}
@media(max-width:600px){
 body{font-size:14px}.shell{width:calc(100% - 30px)}.site-header{height:72px}.hero__grid{padding-top:28px}.hero h1{font-size:42px;line-height:1.02}.hero__copy{line-height:1.6}.hero__actions{flex-direction:column}.button{width:100%}.hero__visual{min-height:190px}.hero-visual-svg{max-width:350px}.eyebrow{font-size:9px;letter-spacing:2px}.section{padding:48px 0}.section-heading{margin-bottom:26px}.section-heading h2{font-size:34px}.card-grid,.cols-2,.cols-3,.cols-4,.cols-5,.cols-6{grid-template-columns:1fr}.info-card{min-height:0;padding:22px 18px}.info-card h3{font-size:24px}.subnav{height:48px}.subnav a{font-size:8px}.hp-row{grid-template-columns:1fr;margin-bottom:26px}.hp-row .stage-line,.hp-note{display:none}.capsule-body{width:235px;height:92px}.capsule-body span{top:27px;right:17px;font-size:10px}.dose-timeline{width:100%}.paper-stack{width:100%;height:235px;transform:scale(.85);transform-origin:center}.record-card{grid-template-columns:1fr}.record-card__thumb{max-width:240px;margin:auto}.record-meta{grid-template-columns:1fr}.viewer-main{display:block}.viewer-outline,.viewer-claims{display:none}.viewer-page-stage{padding:12px;min-height:auto}.viewer-toolbar{font-size:9px;padding:0 10px}.viewer-toolbar__controls{gap:8px}.record-sidebar{grid-template-columns:1fr}.table-wrap{margin-inline:-15px}.site-footer{padding-top:46px}.site-footer__grid{grid-template-columns:1fr}.site-footer__grid>div:not(.footer-brand){display:none}.site-footer__bottom{display:block;line-height:1.7}.form-card{padding:24px 18px}.portal-head{display:block}.portal-head .button{margin-top:16px}.portal-metrics,.folder-grid{grid-template-columns:1fr}.portal-main{padding:18px 12px}.portal-panel{padding:18px}.auth-page{padding:18px}.auth-panel{padding:28px 20px}.auth-panel h1{font-size:38px}
}
.lead-copy{font-size:15px;color:var(--muted);line-height:1.75;margin:0 0 25px}.standalone-heading{font:400 45px/1.08 var(--serif);margin:0 0 26px}.metadata-list{margin:0}.metadata-list dt{font-size:11px;font-weight:700;color:#52627a;border-top:1px solid var(--line);padding-top:16px;margin-top:16px}.metadata-list dd{margin:5px 0 0;color:var(--muted);font-size:12px;line-height:1.55}.dose-lockup{display:grid;grid-template-columns:1fr 1fr;gap:16px;margin:18px 0}.dose-lockup>div{border:1px solid var(--line);padding:20px}.dose-lockup strong{display:block;font:400 48px/1 var(--serif);color:var(--blue)}.dose-lockup small{display:block;color:var(--muted);text-transform:uppercase;letter-spacing:1px;font-size:8px;margin-top:5px}.trial-arms .is-selected{background:linear-gradient(135deg,#3558ff,#7657ff);border-color:transparent;color:#fff}.trial-arms .is-selected .card-number,.trial-arms .is-selected p{color:#fff}.program-focus{display:flex;justify-content:space-between;gap:20px;align-items:flex-start}.program-focus b{color:var(--blue);font-size:11px;max-width:220px;text-align:right}.program-cards--large .info-card{min-height:250px}.sequence-cards{grid-template-columns:repeat(7,1fr)}.sequence-cards .info-card{padding:20px 14px;min-height:180px}.sequence-cards .info-card h3{font:700 13px/1.25 var(--sans)}.sequence-cards .info-card p{font-size:10px}.sequence-cards .card-number{font:700 10px/1 var(--sans);letter-spacing:1px}.evidence-state-cards .info-card{min-height:145px}.evidence-state-cards .info-card::before,.record-type-cards .info-card::before{content:"";width:8px;height:8px;border-radius:50%;background:var(--blue)}.evidence-state-cards .evidence-green::before{background:var(--green)}.evidence-state-cards .evidence-purple::before{background:var(--violet)}.evidence-state-cards .evidence-amber::before{background:var(--amber)}.evidence-state-cards .evidence-gray::before{background:#9da9ba}.evidence-state-cards .evidence-red::before{background:var(--red)}.legal-copy{max-width:900px}.legal-copy h2{font:400 45px/1.1 var(--serif);margin:0 0 25px}.legal-copy h3{font:400 27px/1.2 var(--serif);margin:38px 0 12px}.legal-copy p{color:var(--muted);line-height:1.8}.viewer-shell.is-natural .viewer-page{width:820px;max-width:none}.viewer-toolbar button{border:0;background:transparent;color:#d4dce8;padding:4px 6px}.viewer-toolbar button:hover{color:#fff}.featured-record .record-card{max-width:660px;margin-left:auto}.evidence-feature .record-card{min-width:0}.section-heading+.notice{margin-top:20px}
@media(max-width:1100px){.sequence-cards{grid-template-columns:repeat(4,1fr)}}
@media(max-width:600px){.standalone-heading{font-size:34px}.sequence-cards{grid-template-columns:1fr}.program-focus{display:block}.program-focus b{display:block;text-align:left;margin-top:8px}.dose-lockup strong{font-size:38px}.featured-record .record-card{margin-top:25px}.metadata-list dd{font-size:11px}.viewer-shell.is-natural .viewer-page{width:650px}}
.checkbox-row{display:flex;gap:9px;align-items:center;color:#9dacbf;font-size:11px}.checkbox-row input{width:14px!important;min-height:auto!important}.inline-actions{display:flex;gap:5px;flex-wrap:wrap}.inline-actions button,.data-table form button{border:1px solid var(--line);background:#fff;color:var(--blue);padding:6px 8px;font-size:9px;text-transform:uppercase}.protected-viewer{border:1px solid #b9c6d8;background:#cad3df}.protected-viewer__grid{display:grid;grid-template-columns:180px minmax(0,1fr) 210px;min-height:880px}.protected-outline,.protected-meta{background:#edf1f6;padding:20px;color:#5e6e87;font-size:11px}.protected-outline strong{display:block;color:#263349;margin-bottom:10px}.protected-outline a{display:block;margin:7px 0}.protected-outline hr{border:0;border-top:1px solid #ccd5e2;margin:20px 0}.protected-page-stage{padding:28px;display:flex;justify-content:center;align-items:flex-start}.protocol-page{position:relative;background:#fff;width:min(100%,620px);min-height:820px;padding:78px 70px;box-shadow:0 1px 3px rgba(0,0,0,.12)}.protocol-page h2{font:400 42px/1 var(--serif);margin:38px 0 8px}.protocol-page h3{font:400 28px/1.2 var(--serif);margin:0 0 35px}.protocol-page p{color:#55677f;line-height:1.65}.protocol-page hr{border:0;border-top:1px solid #d3dce8;margin:30px 0}.protocol-page footer{position:absolute;left:70px;right:70px;bottom:50px;border-top:1px solid #d3dce8;padding-top:16px;color:#91a0b5;font-size:9px}.comment-record{border-top:1px solid var(--line);padding:16px 0}.comment-record strong{font-size:10px;color:#697991}.comment-record p{margin:7px 0;color:#4e6078}.auth-panel .notice{margin-top:15px}.portal .stage-line{--stages:6}.portal .button--outline{color:var(--blue);border-color:#93a6ff;background:#fff}.portal .button{width:auto}.portal .info-icon{color:#60728c}.form-field select option{color:#0b1320;background:#fff}
@media(max-width:980px){.protected-viewer__grid{grid-template-columns:1fr}.protected-outline,.protected-meta{display:none}.protocol-page{min-height:760px}.portal .button{width:auto}}
@media(max-width:600px){.protocol-page{padding:40px 25px;min-height:650px}.protocol-page h2{font-size:35px}.protocol-page h3{font-size:22px}.protocol-page footer{left:25px;right:25px;bottom:25px}.portal .button{width:100%}}

/* Comp-specific responsive presentations */
.mobile-design{display:none}
@media(max-width:600px){
 .desktop-design{display:none!important}.mobile-design{display:block}
 .mobile-hero{background:linear-gradient(112deg,#030e1d 0%,#06162c 62%,#0a2450 100%);color:#fff;padding:48px 0 34px;overflow:hidden}
 .mobile-hero .eyebrow{margin-bottom:22px}.mobile-hero h1{font:400 43px/1.02 var(--serif);letter-spacing:-1.2px;margin:0}.mobile-hero h1 em{font-style:normal;color:#7392ff}.mobile-hero>div>p:not(.eyebrow){color:#aebbd0;font-size:14px;line-height:1.6;margin:18px 0 0}
 .mobile-hero__visual{height:185px;display:flex;align-items:center;justify-content:center;margin:20px 0 14px}.mobile-hero__visual svg{width:100%;max-width:330px;height:100%}
 .mobile-actions{display:grid;gap:10px}.mobile-actions .button{min-height:44px}
 .mobile-design+.site-footer{margin-top:0}
 .mobile-section{padding:48px 0}.mobile-section--white{background:#fff}.mobile-section--fog{background:var(--fog)}.mobile-section--dark{background:var(--navy);color:#fff}
 .mobile-section h2{font:400 34px/1.07 var(--serif);letter-spacing:-.8px;margin:0 0 24px}.mobile-section--dark h2{color:#fff}
 .mobile-card{border:1px solid var(--line);background:#fff;padding:18px 14px;margin-top:12px}.mobile-card h3{font:400 24px/1.15 var(--serif);margin:15px 0 8px}.mobile-card p{color:var(--muted);font-size:12px;line-height:1.55;margin:0}.mobile-card .card-tag{width:100%}
 .mobile-evidence-note{background:#fff;color:#63738b;padding:32px 18px;font-size:12px;line-height:1.65;border:1px solid #e2e7ef}
 .mobile-manuscript-card{border:1px solid var(--line);background:#fff;padding:14px}.mobile-manuscript-card img{width:100%;border:1px solid #edf0f4}.mobile-manuscript-card h3{font:400 24px/1.1 var(--serif);margin:14px 0 7px}.mobile-manuscript-card p{color:var(--muted);font-size:11px;margin:0}.mobile-working-tag{border-color:#e4b456!important;color:#9b6800!important;background:#fff8e8!important;margin-top:12px}
 .page-home .status-bar .shell{font-size:7px;line-height:1.4}.page-home .status-bar .info-icon{display:none}
 .mobile-hero--product{padding-bottom:28px}.mobile-hero--product .mobile-hero__visual{height:205px;margin-top:22px}.mobile-capsule-visual svg{max-width:350px}
 .mobile-tabs{height:52px;background:#fff;border-bottom:1px solid var(--line);overflow:hidden}.mobile-tabs .shell{height:100%;display:flex;gap:27px;align-items:center}.mobile-tabs a{height:100%;display:flex;align-items:center;position:relative;text-transform:uppercase;font-size:8px;letter-spacing:.7px;color:#536078}.mobile-tabs a.is-active{color:var(--blue)}.mobile-tabs a.is-active:after{content:"";position:absolute;left:0;right:0;bottom:0;height:2px;background:var(--blue)}
 .mobile-blue-note{border-left:3px solid var(--blue);background:#eef2ff;color:#52647c;padding:20px 20px;font-size:13px;line-height:1.65}
 .mobile-arm-grid{display:grid;gap:12px}.mobile-arm-grid article{border:1px solid var(--line);background:#fff;padding:20px 18px}.mobile-arm-grid h3{font:400 23px/1.15 var(--serif);margin:0 0 8px}.mobile-arm-grid p{color:var(--muted);font-size:12px;margin:0}
 .mobile-monitoring{padding-top:54px}.mobile-monitor-grid{display:grid;gap:12px}.mobile-monitor-grid article{background:#fff;color:#687991;border:1px solid #d9e1ec;min-height:105px;padding:26px 16px;display:flex;align-items:center;font-size:12px;line-height:1.55}
 .mobile-hero--evidence{padding:44px 0 38px}.mobile-hero--evidence h1{font-size:43px}.mobile-hero--evidence>div>p:not(.eyebrow){font-size:14px}
 .mobile-record-metadata{border:1px solid var(--line);padding:18px}.mobile-record-metadata h2{font-size:25px;margin:17px 0 12px}.mobile-record-metadata p{color:var(--muted);font-size:12px;margin:0 0 19px}.mobile-record-metadata p:last-child{margin-bottom:2px}
 .mobile-viewer-section{padding-top:8px}.mobile-viewer{background:#1d2735;padding:0}.mobile-viewer .viewer-toolbar{height:48px}.mobile-viewer-stage{background:#ccd4de;padding:16px;margin:0 10px 10px;max-height:none;overflow:hidden}.mobile-viewer-stage img{width:100%;background:#fff}.mobile-viewer.is-natural .mobile-viewer-stage img{width:650px;max-width:none}
 .mobile-interpret-card{padding:18px;margin-top:12px}.mobile-interpret-card h3{font-size:24px}.mobile-case-tag{border-color:#6acfae!important;color:#168765!important;background:#effbf7!important}.mobile-open-tag{border-color:#e4b456!important;color:#9b6800!important;background:#fff8e8!important}
 .mobile-hero--engage{padding-bottom:26px}.mobile-hero--engage .mobile-hero__visual{height:200px;margin-top:22px}
 .mobile-request-grid{display:grid;gap:12px}.mobile-request-grid article{border:1px solid var(--line);padding:21px 18px}.mobile-request-grid h3{font:400 24px/1.15 var(--serif);margin:0 0 9px}.mobile-request-grid p{color:var(--muted);font-size:12px;line-height:1.55;margin:0}
 .mobile-engage-form{padding:34px 0}.mobile-engage-form .form-card{border-color:#25466f;background:#06162c}.mobile-engage-form .form-card h3{font-size:31px}.mobile-engage-form .form-field textarea{min-height:108px}
 .site-footer{padding:46px 0 34px}.site-footer .footer-brand p:nth-of-type(2){display:none}.site-footer__bottom{margin-top:28px;border:0;padding-top:0}.site-footer__bottom span:first-child{display:none}.site-footer__bottom span:last-child{display:block;max-width:330px;line-height:1.7}
}
@media(max-width:600px){.mobile-design .status-bar .info-icon{display:none}.mobile-design .status-bar .shell{font-size:7px;line-height:1.45}}